ADHD as a Model of Brain-Behavior Relationships by Leonard F. Koziol

By Leonard F. Koziol

ADHD as a version of Brain-Behavior Relationships

Leonard F. Koziol, Deborah Ely Budding, and Dana Chidekel

sequence name: Springer Briefs in Neuroscience

Subseries: The Vertically geared up mind in thought and Practice

It's been a uncomplicated neurological given: the mind does our considering, and has advanced to do the pondering, as managed through the neocortex. during this schema, all disorder may be traced to difficulties within the brain’s lateral interactions. yet in clinical fact, is that this quite actual? tough this conventional cortico-centric view is a physique of analysis emphasizing the position of the buildings that keep an eye on movement-the brain's vertical organization-in behavioral indicators.

Using a widely known, extensively studied illness as a attempt case, ADHD as a version of Brain-Behavior Relationships bargains an cutting edge framework for integrating neuroscience and behavioral examine to refine diagnostic approach and boost the certainty of issues. opting for a profound disconnect among present neuropsychological checking out and how the mind really features, this revision of the paradigm opinions the DSM and ICD when it comes to the connectedness of mind buildings relating to cognition and behaviour. The authors argue for a large-scale mind community method of pathology rather than the localizing that's so universal traditionally, and for another set of diagnostic standards proposed by way of the NIMH. incorporated within the coverage:

  • The analysis of ADHD: heritage and context.
  • ADHD and neuropsychological nomenclature
  • Research area standards: a dimensional method of comparing disorder
  • The improvement of motor abilities, govt functionality, and a relation to ADHD
  • The position of the cerebellum in cognition, emotion, motivation, and dysfunction
  • How large-scale mind networks interact

Heralding a extra actual way forward for evaluate, analysis, and remedy of neurodevelopmental problems, ADHD as a version of Brain-Behavior Relationships represents an enormous breakthrough for neuropsychologists, baby psychologists, and psychiatrists, or any similar career attracted to a neuroscientific realizing of mind function.

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The ‘‘default network,’’ whose activity is high until active, goal-directed cognitive processing is required, is anchored in two regions: the anterior medial prefrontal cortex and the posterior cingulate cortex. There are two additional components to this network, the dorsomedial prefrontal system and the medial temporal lobe memory system. Interestingly, the default network is less active during the performance of cognitive tasks in normal control subjects. In ADHD, these default network regions are recruited and activity is not suppressed.

While the internal circuitry of the neocortex is characterized by its heterogeneity, the infrastructure of the cerebellum is characterized by its homogeneity. This uniformity implies that the computations of the cerebellum result in only one general output operation that the cerebellum performs on whatever afferent information it receives [219, 220]. Whether this information is related to movement, thought, affect, or motivation, the cerebellum regulates its rate, rhythm, and force. In so doing, the cerebellum regulates the quality of behavior by allowing automated behaviors to be adapted to changing situations.

26 Large-Scale Brain Networks and Functional Connectivity The ventral attentional network includes the temporoparietal junction, the supramarginal gyrus, the frontal operculum, and the anterior insula. Afferents from the temporal/parietal lobes also project to the striatum [129]. The ventral attentional network is closely related to circuits referred to as ‘‘the salience network’’ or ‘‘the cingulo-opercular network,’’ as reviewed by Castellanos and Proal [4]. The ventral information-processing stream registers ‘‘what’’ the individual is seeing and has traditionally been referred to as the ‘‘what’’ or object identification pathway [119, 130].

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